This homestyle chicken penne casserole is a comforting, crowd-pleasing dish packed with tender chicken, al dente penne pasta, and a creamy, cheesy sauce. Topped with golden breadcrumbs, it’s perfect for family dinners, potlucks, or meal prep.

---

Ingredients

• 12 oz penne pasta
• 2 cups cooked chicken, shredded or diced (rotisserie chicken works well)
• 2 tablespoon butter
• 2 tablespoon all-purpose flour
• 2 cups milk
• ½ cup chicken broth
• 1 teaspoon garlic powder
• 1 teaspoon Italian seasoning
• ½ teaspoon salt
• ¼ teaspoon black pepper
• 1 cup shredded mozzarella cheese
• ½ cup grated Parmesan cheese
• 1 cup breadcrumbs
• 2 tablespoon olive oil or melted butter (for topping)

---

Instructions

1. Cook the Pasta:
   • Preheat the oven to 375°F (190°C). Cook penne pasta in a large pot of salted boiling water until al dente. Drain and set aside.
2. Make the Creamy Sauce:
   • In a medium saucepan, melt butter over medium heat. Whisk in flour and cook for 1-2 minutes, stirring constantly. Gradually add milk and chicken broth, whisking until smooth. Cook for 4-5 minutes, until the sauce thickens.
   • Stir in garlic powder, Italian seasoning, salt, and pepper. Add ½ cup of mozzarella and Parmesan cheese, stirring until melted and smooth.
3. Combine the Ingredients:
   • In a large mixing bowl, combine cooked pasta, shredded chicken, and the creamy sauce. Mix until evenly coated.
4. Assemble the Casserole:
   • Transfer the mixture to a greased 9x13-inch baking dish. Top with the remaining ½ cup of mozzarella cheese.
5. Add the Topping:
   • In a small bowl, combine breadcrumbs with olive oil or melted butter. Sprinkle the mixture evenly over the casserole.
6. Bake:
   • Bake for 25-30 minutes, or until the top is golden and the casserole is bubbling around the edges.
7. Serve:
   • Let cool for 5 minutes before serving. Garnish with fresh parsley, if desired.

---

Tips for the Best Chicken Penne Casserole

• Use rotisserie chicken: It saves time and adds extra flavor.
• Make it ahead: Assemble the casserole and refrigerate it overnight. Bake just before serving.
• Add veggies: Mix in spinach, broccoli, or mushrooms for extra nutrition.

---

Nutrition (Per Serving, Approx. 6 Servings)

• Calories: 430
• Fat: 16g
• Saturated Fat: 7g
• Cholesterol: 80mg
• Sodium: 540mg
• Carbohydrates: 45g
• Fiber: 2g
• Protein: 28g